Follow the signs to Roma Termini station. From the station, find the exit on Via Marsala cross the street and in front of you, Via Marghera, after four blocks, turn right on Via Palestro.
Roma Termini station. Eurostar link to Florence, Milan, Venice and Naples. The hotel is just a 10 minute taxi ride from the station.
The Rome airport (FCO) connects the city to major destinations in Europe and other continents. The hotel is 25 minutes by taxi from the airport.